When the stimulus intensity is a half of the value that induced the largest response of synapses , the paired - pulse stimulation of 75 - ms interval produced a stable ppd while the stimulation of 150 - ms or 300 - ms produced a stable ppf 在1 2最大反應(yīng)強度為檢測刺激時,間隔為75ms時可產(chǎn)生穩(wěn)定的ppd ,而間隔為150ms和300ms時則可產(chǎn)生穩(wěn)定的ppf 。
In the presence of l - isoproterenol ( through local infusion into area ca1 ) , the theta - pulse stimulation with the parameter of 10 hz , 150 pulses / train , 1 train , a frequency weakly modifying synaptic strength , induced a robust ltp , and this effect was blocked when dl - propranolol was co - administered . by contrast , the theta - pulse stimulation with the parameter of 5 hz , 150 pulses / train , 3 train , a frequency strongly modifying synaptic strength , induced a significantly smaller ltp when dl - propranolol was administered into area ca1 正常情況下對突觸傳遞效能僅有微小調(diào)制作用的10hz的(節(jié)律刺激(每串150個脈沖, 1串) ,在ca1區(qū)局部給予l -異丙腎上腺素后,顯著地誘導(dǎo)出ltp ,這一效應(yīng)可被dl -心得安所阻斷;相反,正常情況下對突觸傳遞強度有顯著調(diào)制作用的5hz的(節(jié)律刺激(每串150個脈沖, 3串) ,在ca1區(qū)局部給予dl -心得安后,所誘導(dǎo)出的ltp被顯著壓抑。